A standard Ethernet NIC card (DTE) has the following RJ-45 modular pinout:
Pin Function 1 Tx+ 2 Tx- 3 Rc+ 6 Rc-
The RJ-45 modular jack has 8 conductors/pins. Viewed from the front:
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TIA-568B
TIA-568B is the most common wiring scheme used in 10/100BaseT configurations. The standard Ethernet "Patch" cable that connects a hub port to a NIC card uses TIA-568 wiring at both ends of a "straight-through" cable:

In TIA-568A wiring schemes, the White/Orange and White/Green pairs are transposed. An Ethernet "Crossover" cable can be made by using TIA-568B at one end of the cable and wiring to TIA-568A at the other end of the cable. These "Crossover" cables can be used to interconnect NIC cards directly, without the need for a hub. "Crossover" cables are usually "RED" in color:

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